Eduard Kraft principal research topic is the anatomical and physiological basis of functional recovery processes and the rehabilitation of neurological patients. He is also interested in the neural mechanisms of reasoning, problem solving and executive functions in patients with neurodegenerative disorders, focal lesions and aging. Current studies are focused on reorganization of the representation of cortical and subcortical areas and the effect of interventions in the functional recovery. Another focus is the functional anatomy of executive functions (working memory, problem solving) in neurodegenerative disorders and focal brain lesions. Research involves patients with stroke, neurodegenerative disorders (e.g. Parkinson´s disease, Amyotrophic lateral sclerosis), complex regional pain syndrome, but also patients with focal brain lesions (for instance, frontal brain tumors). In 1997–1999 he was granted a Research Fellowship at the NMR Center (now Martinos Center for Biomedical Imaging) at the Massachussetts General Hospital and Harvard Medical School (Boston), where he spent two years working with Kenneth Kwong and Bruce Jenkins.

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Eduard Kraft is Member of the German Society of Neurology, of the International Movement Disorders Society and of the Organization for Human Brain Mapping.